| L | May 1May 1, 2022 | SYNTAINICS MBC vs Veolia Towers HamburgBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 30 | 8 | 5 | 1 | 2 | 2 | 22.2% | 50.0% |
| W | Apr 29Apr 29, 2022 | SYNTAINICS MBC vs Basketball Löwen BraunschweigBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 26 | 4 | 6 | 2 | 2 | 0 | 16.7% | 66.7% |
| L | Apr 23Apr 23, 2022 | Fitness First Würzburg Baskets vs SYNTAINICS MBCBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 30 | 14 | 6 | 1 | 4 | 0 | 41.7% | 100.0% |
| L | Apr 17Apr 17, 2022 | SYNTAINICS MBC vs NINERS ChemnitzBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 30 | 13 | 9 | 0 | 1 | 0 | 35.7% | 50.0% |
| L | Apr 13Apr 13, 2022 | FC Bayern München Basketball vs SYNTAINICS MBCBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 30 | 4 | 4 | 0 | 1 | 0 | 20.0% | 100.0% |
| L | Apr 10Apr 10, 2022 | SYNTAINICS MBC vs Alba BerlinBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 29 | 11 | 7 | 1 | 0 | 0 | 50.0% | 50.0% |
| W | Apr 6Apr 6, 2022 | HAKRO Merlins Crailsheim vs SYNTAINICS MBCBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 37 | 17 | 8 | 2 | 0 | 1 | 63.6% | 0.0% |
| L | Apr 2Apr 2, 2022 | ratiopharm ulm vs SYNTAINICS MBCBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 33 | 22 | 8 | 1 | 3 | 0 | 44.4% | 33.3% |
| L | Mar 30Mar 30, 2022 | MHP RIESEN Ludwigsburg vs SYNTAINICS MBCBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 29 | 18 | 9 | 4 | 1 | 0 | 50.0% | 60.0% |
| L | Mar 26Mar 26, 2022 | SYNTAINICS MBC vs Telekom Baskets BonnBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 25 | 11 | 5 | 1 | 1 | 0 | 50.0% | 60.0% |
| L | Mar 20Mar 20, 2022 | BMA365 Bamberg Baskets vs SYNTAINICS MBCBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 33 | 11 | 6 | 0 | 0 | 0 | 55.6% | 0.0% |
| W | Mar 17Mar 17, 2022 | SYNTAINICS MBC vs GIESSEN 46ersBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 36 | 15 | 13 | 1 | 3 | 0 | 53.8% | 50.0% |
| W | Mar 13Mar 13, 2022 | SYNTAINICS MBC vs SKYLINERSBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 23 | 2 | 5 | 1 | 1 | 2 | 14.3% | 0.0% |
| W | Mar 5Mar 5, 2022 | SYNTAINICS MBC vs BBC BayreuthBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 31 | 17 | 9 | 2 | 2 | 0 | 70.0% | 50.0% |
| L | Feb 16Feb 16, 2022 | MLP Academics Heidelberg vs SYNTAINICS MBCBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 30 | 8 | 3 | 2 | 2 | 0 | 50.0% | 33.3% |
| L | Feb 13Feb 13, 2022 | EWE Baskets Oldenburg vs SYNTAINICS MBCBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 27 | 11 | 7 | 0 | 1 | 1 | 66.7% | 100.0% |
| W | Jan 23Jan 23, 2022 | SYNTAINICS MBC vs BG GöttingenBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 31 | 13 | 7 | 3 | 2 | 1 | 66.7% | 0.0% |
| W | Jan 18Jan 18, 2022 | SYNTAINICS MBC vs EWE Baskets OldenburgBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 34 | 15 | 11 | 3 | 0 | 2 | 50.0% | 60.0% |
| L | Jan 14Jan 14, 2022 | Veolia Towers Hamburg vs SYNTAINICS MBCBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 37 | 27 | 10 | 2 | 1 | 0 | 64.7% | 60.0% |
| L | Jan 8Jan 8, 2022 | SYNTAINICS MBC vs ratiopharm ulmBasketball Bundesliga (BBL) | Basketball Bundesliga (BBL) | 30 | 11 | 7 | 0 | 0 | 1 | 30.8% | 100.0% |
